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Titrating the dose slowly as done in clinical trials appears to reduce both frequency and severity

Matrigel coating of organoids with iPSC-derived ECs from the same individual reportedly results in a vascularized brain organoid (Pham et al., 2018)

Each component underwent Phase I/II clinical trials but did not proceed to further development

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Blockade of type A, not type B, CCK receptors attenuates satiety actions of exogenous and endogenous CCK